The corporate responsibility to respect human rights means to avoid infringing on the rights of others and addressing adverse impacts that may occur. This responsibility applies across an enterprise’s activities and through its relationships with other parties, such as business partners, entities in its value chain, other non-state actors and state agents. Suppliers have the same responsibility to respect human rights as any other business entity. However, this note focuses on enterprises that purchase goods and services from suppliers. It outlines a decision logic for them to manage adverse human rights impacts in their supply chains and meet their responsibility to respect human rights.